You can remove pothos leaves by hand. But using a knife, pruning shears, or sharp scissors will give you the tidiest cut. Once you’ve selected your pruning tool, sterilize the shears by wiping them with 70-100% isopropyl alcohol.
The next step is deciding where on the plant you want to cut. The best cut location depends on what you hope the pruning will achieve.
Once you’ve selected the general area of the pothos you want to prune, you need to find the node. The leaf node is a small brown bump on the stem. It is the point from which new leaves and new stems grow.