There are several scientific thoughts on the reasons for foliage fenestration. One is that wind can move through the large leaves without damaging them. Another theory is that the holes allow for more surface area to cool the leaves and to better capture light.
In order for your plants to get to the point where they will develop those coveted splits and holes in their leaves, you’ll have to allow them to climb.
To make your own moss pole, moisten the sphagnum moss, fluff it up, and lay it along the length of wire mesh. Roll the mesh into a tube and secure it with cable ties.
The answer is yes and no. It may take years, but when Pothos plants are allowed to mature, they will begin to fenestrate.