Pothos grows best in temperatures of 65 to 90 degrees Fahrenheit. It will die in temperatures below 50 degrees, become stressed, and cook in temperatures above 90 degrees.
Just like in tropical rainforests, Pothos plants thrive with humidity in the 50% to 70% range. They are tolerant of lower humidity, but the highly variegated cultivars, such as N’ Joy, Pearls and Jade, Marble Queen, and Harlequin, need higher humidity levels than their less variegated varieties.
In its native rainforest habitat, Pothos grows on the ground and climbs up a tree if it encounters one as it trails along. The light that it gets through the trees is filtered, dappled sun or bright shade – never direct sunlight.